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. 2018 Jun 5;10(6):1206–1222. doi: 10.18632/aging.101461

Table 2. The longevity CNVRs and their encoded genes.

CNVR(hg19) Cytoband Type p value Odds Ratio Frequency in long-lived% Frequency in middle-aged% Gene encoded CNVR Length(kb)
chr7:57787663-57839005 7p11.2 Dup 8.67×10-7 1.59 15.90 5.74 ZNF716 51.34
chr19:22145147-22231026 19p12 Dup 1.89×10-6 4.11 2.36 0.63 ZNF208,ZNF257 85.88
chr13:100620882-100630973 13q32.3 Del 2.88×10-6 3.88 2.41 0.63 ZIC5,ZIC2 10.09
chr11:2939050-2949861 11p15.4 Del 6.24×10-6 4.81 1.85 0.39 PHLDA2,SLC22A18 10.81
chr4:1610872-1621223 4p16.3 Del 6.51×10-6 12.21 1.18 0.10 FAM53A 10.35
chr9:130479233-130504070
chr20:60900481-60927421
9q34.11
20q13.33
Del
Del
6.76×10-6
4.42×10-5
21.3
10.65
1.03
1.08
0.05
0.10
PTRH1,SH2D3C,TOR2A,TTC16
LAMA5
24.84
26.93
chr8:1789006-1799964 8p23.3 Del 4.45×10-5 10.65 1.03 0.15 ARHGEF10 10.96
chr21:38442208-38453183 21q22.13 Del 4.90×10-5 5.16 1.54 0.29 PIGP,TTC3 10.98
chr14:38058065-38081005 14q21.1 Del 8.43×10-5 4.57 1.54 0.34 TTC6,FOXA1 22.94
chr15:96898166-96909819 15q26.2 Del 8.43×10-5 4.57 1.54 0.34 NR2F2 11.65