Table 3. Longevity genes and pathways enriched in the genomes.

Database Category	Term	Genes	p-value
GOTERM_BP_FAT	epithelium development	ZIC2,ZIC5,FOXA1,LAMA5,NR2F2	1.2×10-4
GOTERM_BP_FAT	tube morphogenesis	ZIC2,ZIC5,FOXA1,LAMA5	4.1×10-4
GOTERM_BP_FAT	tube development	ZIC2,ZIC5,FOXA1,LAMA5	2.0×10-3
GOTERM_BP_FAT	morphogenesis of embryonic epithelium	ZIC2,ZIC5,LAMA5	2.1×10-3
GOTERM_BP_FAT	epithelial tube morphogenesis	ZIC2,ZIC5,LAMA5	2.8×10-3
Biological pathway	FOXA1 transcription factor network	FOXA1,NR2F2	1.30×10-3
Biological pathway	Mesenchymal-to-epithelial transition	PHLDA2,SLC22A18,FOXA1	2.16×10-3
Biological pathway	FOXA transcription factor networks	FOXA1,NR2F2	4.36×10-3
Biological pathway	Alpha6 beta4 integrin-ligand interactions	LAMA5	1.39×10-2
Biological pathway	Synthesis of glycosylphosphatidylinositol (GPI)	SLC22A18	2.14×10-2
Biological pathway	Post-translational modification: synthesis of GPI-anchored proteins	PIGP	3.26×10-2