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. 2018 Jun 5;10(6):1206–1222. doi: 10.18632/aging.101461

Table 4. The CNVRs commonly shared in three ethnic groups.

Han Chinese Danish U.S. ‘wellderly’
CNVR Cytoband Type Frequency(%) CHB Gene encoded CNVR Type Frequency(%) EUR gene Overlap% Type Frequency(%) AMR
Chr20:60900481-60927412 20q13.33 DEL 1.07 0 LAMA5 Chr20:60872280-60909518 DEL 0.33 0 20* NA NA NA NA
Chr19:22145147-22231026 19p12 DUP 2.36 0 19* NA NA NA NA 9 DUP 0.1 0

Among all the Han Chinese longevity CNVRs, two were found overlapping with the longevity CNVRs yielded from the Danish study and three from the US study (one shared in both Danish and US study). However, only one of these four attained a larger than 1% frequency. Bold indicates the CNVRs with at least 5% overlapping regions among the three long-lived ethnic groups. NA: the absence of CNVR. Frequency %: the occurrence of the CNVRs among the investigated samples. CHB, EUR, AMR represent Chinese, Europeans, and ad mix Americans in the 1000 genomes database (phase 3). 19*, 20*, and 7* indicate the regions that contain the genes, ZNF208 and ZNF257, ADRM1 and LAMA5, and GUSBP10, LOC105375297, ZNF716, and MIR3147, respectively.