Table 3. Cytokine levels in non-senescent and doxorubicin-senescent cells in response to JAK inhibitors.

		Water			JAKI			HNG			HNG+JAKI
		Mean	SE		Mean		SE	Mean		SE	Mean	SE
IL-6	NS	2.70	0.15		1.96		0.08	1.96		0.17	2.78	0.35
	SEN	10.27	0.56		9.19		0.65	12.61*		0.27	9.19	0.65
IL-1 beta	NS	1.57	0.09		1.58		0.09	1.59		0.23	1.95	0.15
	SEN	6.94	0.57		8.15		0.26	6.83		0.15	8.838*	0.76
IL-8	NS	1.61	0.03		1.249***		0.04	1.63		0.08	1.78	0.01
	SEN	2.27	0.03		2.42		0.03	2.34		0.03	2.42	0.02
IL-10	NS	0.56	0.06		0.81		0.14	0.76		0.18	0.63	0.05
	SEN	2.31	0.10		3.88***		0.32	3.376**		0.27	3.356**	0.08
TNFalpha	NS	2.29	0.14		2.97		0.30	3.304		0.31	2.818	0.23
	SEN	8.90	0.10		13.11***		0.46	10.77*		0.56	12.57***	0.65

*<0.05, **<0.01, ***<0.001

IL-8 unit is µg/ml, and other cytokines units are pg/ml.