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. 2018 Jun;6(12):247. doi: 10.21037/atm.2018.04.42

Figure 1.

Figure 1

HGF/c-Met signaling pathway and therapeutic intervention points. c-Met, hepatocyte growth factor receptor; HGF, hepatocyte growth factor; SEMA, semaphorin; PSI, plexin, semaphorin and integrin; IPT, immunoglobulin-like regions in plexins and transcription factors; JM, juxtamembrane; TK, tyrosine kinase; MFDS, multifunctional docking site; mAbs, monoclonal antibodies; TKIs, tyrosine kinase inhibitors.