Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jul 9;5:81. doi: 10.3389/fcvm.2018.00081

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Moss, DuPont, Iyer, McGraw and Jaffe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

SMC-MR deletion does not alter aortic root plaque size or composition in young ApoE^−/− mice after 8 weeks of high fat diet. Representative histological images are shown for aortic root sections stained with: (A) Oil Red O (ORO); (B) PicroSirius Red for collagen; (C) Mac2/Galectin-3 immunofluorescence; and (D) Smooth muscle α-actin (SM-Actin) immunofluorescence, with the Mac2 and SM-Actin merged images shown in (E). Plaque area is quantified in (F) along with plaque composition, including lipid content and necrotic core area. (G) Collagen content, (H) Mac2 positive area, and (I) SM-Actin positive area are quantified. Plaque composition data are expressed relative to the percent of each component in plaques from MR-Intact animals. All comparisons were not significant (p > 0.05) by unpaired student's t-test. Scale bars = 200 μm.