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. 2018 Jul 9;12:457. doi: 10.3389/fnins.2018.00457

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Copyright © 2018 Guo, Zhu, Wang, Zhang, Wang, Sun, Li, Xue, Gu and Cui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic diagram of the transcriptional changes for both immune response and axonal regeneration following sciatic nerve transection. (A) Dynamic changes (top 5) of differentially expressed genes for immune response, guidance of axons, growth of axons, branching of axons and regeneration of axons (red color code for up-regulated genes, green color code for down-regulated genes). (B) PPI network of selected genes for axonogenesis, branching of axons, extension of axons, guidance of axons, guidance of motor axons, projection of axons, growth of axons, outgrowth of axons, penetration of axons and immune response.