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Effect of PTPN22-siRNA on miR-181a expressions in Jurkat cell line. After transfection with 80 pmol of PTPN22-siRNA and 48 hrs after transfection, RNA was extracted and the expression of miR-181a was detected by qRT-PCR. **** indicates a significantly decrease in miR-181a levels in Jurkat cells following transfection with PTPN22-siRNA (80pmol dose) compared with the control group cells (P <0.001).
