Table 1. Solubility, partition coefficient and lipid partitioning of nicotinamide.
| Solubility | ||||
| NA in water(mg/ml) | NA in n-octanol (mg/ml) | |||
| Preliminary test | 714.28 | 4.347 | ||
| Main test | 735.10 | 4.61 | ||
| Partition Coefficient | ||||
| n-octanol:water | NA in water | NA in n-octanol | Partition coefficient | |
| 1:1 | Test1 | 0.679 | 0.291 | 0.43 |
| Test2 | 0.692 | 0.277 | 0.40 | |
| 1:2 | Test1 | 0.787 | 0.370 | 0.47 |
| Test2 | 0.791 | 0.387 | 0.49 | |
| 2:1 | Test1 | 0.708 | 0.262 | 0.37 |
| Test2 | 0.717 | 0.258 | 0.36 | |
| Lipid Partitioning | ||||
| SA:GMS | PC lipid/water | |||
| 1:0 | 0.24 | |||
| 0:1 | 0.14 | |||
| 1:1 | 0.18 | |||
| 2:1 | 0.26 | |||
| 3:1 | 0.12 | |||
| 1:2 | 0.16 | |||
| 1:3 | 0.11 | |||
*NA= Nicotinamide, SA=Stearic acid, GMS= Glyceryl monostearate, PC=Partition coefficient.