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. 2018 Jul 9;9:745. doi: 10.3389/fphar.2018.00745

Table 1.

Overview of NPs designed for urological cancer treatments.

Cancer types Treatment strategies Applied NPs Reference
Prostate cancer Chemotherapy GNPs loaded with chrysophanol Lu et al., 2017
EGCG-encapsulated polymeric NPs modified with PSMA Sanna et al., 2011
Gene therapy Polymeric NPs loaded with GS25 Voruganti et al., 2015
GNPs loaded with miRNA Ekin et al., 2014
Thermal therapy MNPs and GNPs Johannsen et al., 2007a, 2010
Renal cancer Targeted therapy Sorafenib-loaded PLGA NPs, DPPC liposomes and HMC-coated DPPC liposomes Liu et al., 2015a,b
Gene therapy FA-PEAs:VHL complexes Sudimack and Lee, 2000
Thermal therapy PEGylated gold nanoshells Pannerec-Varna et al., 2013
MWCNTs Burke et al., 2009
PDT GNPs with radiofrequency radiation Nikzad et al., 2017
Targeted therapy Cuprous oxide nanoparticles Yang et al., 2017
Superparamagnetic-like particles Leulmi et al., 2015
Bladder cancer Immunotherapy Liposomes encapsulating BCG’s CWS Nakamura et al., 2014
Gene therapy PEGylated cationic liposome carriers (PCat, PPCat) and modified PLGA NPs delivering siSurvivin Martin et al., 2014; Cui et al., 2015
Targeted therapy PLGA NPs loaded with belinostat Martin et al., 2013
Chemotherapy Paclitaxel-loaded protein NPs Lu et al., 2011; McKiernan et al., 2011
PTT GNPs Chen et al., 2015b
Silica-Au nanoshells, Au/Ag nanospheres, and Au nanorods modified with tumor targeting antibodies Juarranz et al., 2008; Cheng et al., 2009
NP-AAG Long et al., 2018