Table 2.
The expression of regulatory cytokines and death‐signal markers (MFI) in primary and activated CD5low vs. CD5hi B cells.
Primary | Activated | |||||
---|---|---|---|---|---|---|
CD19+CD5low | CD19+CD5hi | P‐value | CD19+CD5low | CD19+CD5hi | P‐value | |
FasL | 4·14 ± 2·0 | 12·18 ± 2·77 | P < 0·0001 | 11·58 ± 3·59 | 32·03 ± 8·65 | P < 0·0001 |
Interleukin‐10 | 2·37 ± 1·04 | 5·41 ± 1·82 | P = 0·0003 | 18·36 ± 4·15 | 36·44 ± 5·45 | P < 0·0001 |
Granzyme B | 2·07 ± 0·80 | 11·59 ± 8·94 | P < 0·0001 | 8·48 ± 3·77 | 27·68 ± 12·98 | P < 0·0001 |
Perforin | 1·82 ± 1·02 | 4·15 ± 2·25 | P = 0·0069 | 1·33 ± 0·48 | 6·98 ± 2·34 | P < 0·0001 |