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. 2018 May 16;193(2):167–177. doi: 10.1111/cei.13138

Figure 2.

Figure 2

Evolutionary history and human genomic position of the FAM167 gene and disordered autoimmunity (DIORA) protein family. (a) Phylogenetic tree generated using FAM167A as seed sequence and (b) DIORA protein sections present in the different species (PhylomeDB). Homologues with predicted Domain of Unknown Function (DUF)3259 domains were included, the position of which is indicated for each species. Amino acid colouring according to the standard scheme of PhylomeDB. (c) Phylum/class/order of respective species. (d,e) Location of FAM167A and FAM167B and neighbouring genes on chromosomes 8p23.1 and 1p35.2–35.1, respectively, in the human genome [University of California Santa Cruz (UCSC) genome browser].