. 2018 May 16;193(2):167–177. doi: 10.1111/cei.13138

Table 1.

Predicted characteristics of the FAM167 genes and their encoded DIORA proteins

	FAM167A/DIORA‐1	FAM167B/DIORA‐2
Synonyms*	C8orf13, D8S265	C1orf90
Paralogues ^†	1 (FAM167B)	1 (FAM167A)
Gene position ^†	8p23.1	1p35.1
Exons ^†	4	2
Transcripts/splice variants ^†	7 (701–4094) bp	1 (936 bp)
Protein coding transcripts ^†	4	1
Protein length ^‡	214 aa	163 aa
Differently spliced protein ^†	91 aa	–
Molecular weight (full‐length) ^‡	24·2 kD	18·4 kD
Isoelectric point ^§	5·93	5·28
Atomic composition ^¶	C₁₀₅₂H₁₆₉₇N₃₁₅O₃₂₃S₈	C₇₉₈H₁₂₉₅N₂₃₉O₂₄₅S₈
Negatively charged aa (Asp + Glu) ^¶	33	26
Positively charged aa (Arg + Lys) ^¶	29	20
Instability index (II) ^¶	62·96 (unstable)	66·36 (unstable)
Aliphatic index ^¶	82·20	92·33
Grand average of hydropathicity ^¶	−0·639	−0·491
Protein family** (aa)	PF11652 (130–214)	PF11652 (90–163)
DUF* (aa)	DUF3259 (130–214)	DUF3259 (90–163)
Coiled coil** (aa)	134–154	73–93
Disorder ^††	1–28; 57–109	10–25; 57–61
Phosphorylation sites ^§	6	1
Transmembrane region ^‡‡	0	0
Nuclear localization signal ^§§	0	0

Information source: *GPSDB Gene/Protein Synonyms finder. ^†Ensembl. ^‡UniProt. ^§PhosphositePlus. ^¶ProtPram. **Pfam. ^††D2P2. ^‡‡SCRATCH/ABTMpro. ^§§NucPred.

aa = amino acid; bp = base pairs; DUF = Domain of Unknown Function; kD = kilodalton.