Table 1.

Unadjusted association between PIMs or PPOs and study variables and outcomes

		STOPP	START
		Unadjusted OR of at least 1 PIM (95% CI)	Unadjusted OR of at least 1 PPO (95% CI)
Sex (ref: male)	Female	1.29 (0.79–2.13)	0.74 (0.44–1.26)
Age (ref: ≥80 years)	65–79 years	1.05 (0.63–1.77)	0.72 (0.41–1.26)
Number of discharge medications (ref: <5)	6–10	2.65 (1.31–5.36)**	3.29 (1.62–6.67)**
	>10	4.42 (2.05–9.53)***	3.13 (1.47–6.66)**
Number of comorbidities (ref: ≤5)	>5	2.21 (1.33–3.68)**	1.96 (1.14–3.39)*
Number of readmissions (ref: 0)	1–2	1.30 (0.67–2.51)	1.00 (0.50–2.01)
	≥3	2.53 (1.26–5.08)**	1.61 (0.77–3.36)
Mortality at follow‐up (ref: alive)	Deceased	1.15 (0.70–1.89)	1.96 (1.14–3.35)*

^* = P < 0.05,

^** = P < .001,

^*** = P < 0.0001 on univariate analysis