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Plasma PF‐04965842 concentration vs. time profiles. (A) SAD phase. Data for 1 subject in the 800 mg (western) group were excluded due to vomiting. (B) MAD phase. Data shown are for day 10 predose (0 h) up to 72 h postdose. Data for 1 subject in the 400 mg QD group were excluded due to vomiting. BID, twice daily; MAD, multiple ascending dose; PK, pharmacokinetic; QD, once daily; SAD, single ascending dose
