Figure 2.

Relative abundance of (anti)coagulation proteins in platelets and plasma. Shown are the protein copy numbers (kCopy) of indicated (anti)coagulant factors per platelet (grey) as determined by mass spectrometry.110 In addition, average factor levels in normal plasma (×10−8 mol L−1, black). For FVIII, the platelet copy number refers to the F8 transcript F8I2. HMWK, high molecular weight kininogen; VWF‐m, VWF‐monomers; TSP1, thrombospondin 1; TFPI, tissue factor pathway inhibitor