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. 2018 Jul 9;8:254. doi: 10.3389/fonc.2018.00254

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Copyright © 2018 Gibellini, Losi, De Biasi, Nasi, Lo Tartaro, Pecorini, Patergnani, Pinton, De Gaetano, Carnevale, Pisciotta, Mariani, Roncucci, Iannone, Cossarizza and Pinti.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LonP1 is upregulated in CRC tissues. (A) Representative immunohistochemical staining of LonP1 in paraffin-embedded human colorectal cancer (CRC) tissue and patient-matched adjacent normal mucosa. (B) Representative immunohistochemical stainings of LonP1 high or low level overexpression in paraffin-embedded human CRC tissues. (C) Representative Western blot analysis of LonP1 expression in CRC tissues and normal mucosa. (D) Relative protein levels of LonP1 are significantly higher in CRC tissues than in adjacent normal mucosa. Data are reported as mean ± SD (n = 21); *P < 0.05.