Fig. 4.

Effect of KPA on NF-κB transcriptional activity. Effect of KPA on NF-κB luciferase reporter assay in HEK 293 T cells. Cells were co-transfected with pRL-SV-40 plasmid and NF-κB luciferase reporter plasmid for 24 h. And then, cells were treated various concentration of KPA (25-100 μM). Luciferase activities was measured by firefly and Renilla luciferase reporter. Values represent the mean ± SD of three independent experiments and statistical significant values are indicated (*p < 0.05, compared with LPS-stimulated group).