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Sweetener binding in CA IX-mimic. (A) Sucralose (pink), (B) sucrose (yellow, PDB: 4YWP), (C) saccharin (green, PDB: 4RIV), and (D) ace K (blue, PDB: 5WGP). Hydrogen bonds are represented by black dashes (lengths given in Angstroms), and active site residues are labeled.
