Table 2. R1 Group SAR of 1-Methyl-5-oxo-2,5-dihydro-1H-pyrrole core (compounds 7a and 8–12).
IC50 values are an average of at least two independent determinations.
See Supporting Information for standard deviations.
ND = not determined.
IC50 values are an average of at least two independent determinations.
See Supporting Information for standard deviations.
ND = not determined.