Table 5. R3 Group SAR of 1-Methyl-5-oxo-2,5-dihydro-1H-pyrrole Core (Compounds 6a, 6e–g, and 7b–d).
IC50 values are an average of at least two independent determinations.
See Supporting Information for standard deviations.
ND = not determined.
IC50 values are an average of at least two independent determinations.
See Supporting Information for standard deviations.
ND = not determined.