Table 3. Colistin Potentiation by Select Compounds against Gram-Negative Bacteria, Colistin MIC (Fold Reductions)a.
| colistin MIC | colistin + 1 | colistin + 9d | colistin + 13f | |
|---|---|---|---|---|
| E. coli ATCC 25922mcr-1 | 8 | 4 (2) | 0.5 (16) | 2 (4) |
| E. coli ATCC 25922parent | 0.5 | 0.5 (0) | 0.0625 (8) | 0.03125 (16) |
| A. baumannii 17978mcr-1 | 16 | 0.5 (32) | 0.125 (128) | 4 (4) |
| A. baumannii 17978parent | 1 | 0.5 (2) | 0.0625 (16) | 0.0625 (16) |
| A. baumannii 4106 | 1024 | 16 (64) | 2 (512) | 16 (64) |
| K. pneumoniae B9 | 512 | 16 (64) | 1 (512) | 1 (512) |
| A. baumannii 5075 | 1 | 0.25 (4) | 0.0625 (16) | 0.0078 (128) |
| K. pneumoniae ATCC 2146NDM-1 | 1 | 0.5 (2) | 0.0625 (16) | 0.0625 (16) |
a
Concentrations are shown in μg/mL.