Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Superposition of WT-1 and (a) WT-12b, (b) WT-12c, and (c) WT-12d complexes, focusing on the differences at the P2 quinoxaline. The protease is in a ribbon representation (light gray), with bound inhibitors 1 (blue) and 12b–d (orange) depicted as sticks. The side chains of the catalytic triad and drug resistance residues Arg155, Ala156, and Asp168 are shown as balls and sticks.
