Table I.
Strain | Deficiency | Survivors/Total (% Survival) |
---|---|---|
Wild-type | None | 18/20 (90%) |
rag1−/− | B and T cells | 6/16a (37%) |
TCRβδ−/− | T cells | 15/15 (100%) |
μMT−/− | Mature B cells | 7/11a (63%) |
JH−/− | Mature B cells | 12/20a (60%) |
Survival was significantly different from wild-type mice as measured by the log-rank (Mantle–Cox) test.