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. 2018 Jul 16;9:52. doi: 10.1186/s40104-018-0267-8

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Mean (± SEM) concentration of plasma LH (panel A) and GnRH in the ME (panel B) after icv administration of CD14/TLR4 antagonist during central inflammation induced by icv administration of LPS. Different lowercase letters (a, b) indicate significant differences between groups at P < 0.05 (one-way ANOVA followed by Tukey’s post hoc test)