Table 2. Genotype and allele frequency of ATP-binding cassette transporter A1 C-565T polymorphism in patients with CAD and control subjects.
C-565T polymorphism | CAD n = 110 |
Control n = 110 |
OR | 95% CI | p-value |
---|---|---|---|---|---|
Genotypes | |||||
CC | 47 (42.7) | 60 (54.5) | Ref | - | - |
CT | 48 (43.6) | 45 (40.9) | 1.36 | 0.78–2.38 | 0.321* |
TT | 15 (13.6) | 5 (4.5) | 3.83 | 1.29–11.30 | 0.014 |
Alleles | |||||
C allele | 142 (64.5) | 165 (75.0) | Ref | - | - |
T allele | 78 (35.4) | 55 (25.0) | 1.65 | 1.09–2.49 | 0.017 |
CAD: coronary artery disease; CC: wild-type; CT: heterozygote; TT: homozygote; OR: odd ratio; CI: confidence interval. *Statistical power = 27.8%. n (%).