Table 4. Radiological, endoscopic and histopathological investigations of 51 pediatric patients with Crohn’s disease.
Investigations | Positive tests, n (%) | Tested patients, n (%) |
---|---|---|
Radiological | ||
Abdominal ultrasound | 17 (45.9) | 37 (72.5) |
Barium study | 24 (72.3) | 33 (64.7) |
Abdominal CT scan | 13 (92.9) | 14 (27.5) |
Abdominal and pelvic MRI scan | 1 (50.0) | 2 (3.9) |
Endoscopic | ||
OGD | 13 (32.5) | 40 (78.4) |
Colonoscopy | 36 (81.8) | 44 (86.3) |
Area of involvement | ||
Terminal ileum | 32 (68.1) | 47 (92.2) |
Colon | 30 (63.8) | 47 (92.2) |
Stomach | 24 (51.1) | 47 (92.2) |
Small bowel | 23 (48.9) | 47 (92.2) |
Esophagus | 19 (40.4) | 47 (92.2) |
Perianal disease | 8 (17.0) | 47 (92.2) |
Histopathological | ||
Upper gastrointestinal biopsies | 31 (91.2) | 34 (66.6) |
Colon and terminal ileum biopsies | 40 (95.2) | 42 (82.4) |
Chronic mucosal inflammation | 27 (67.5) | 40 (48.4) |
Non-caseating granuloma | 15 (37.5) | 40 (48.4) |
Cryptitis | 15 (37.5) | 40 (48.4) |
Focal non-specific ulcerations | 14 (35.0) | 40 (48.4) |
Crypt abscesses | 11 (27.5) | 40 (48.4) |
Prominent lymphoid follicles | 9 (22.5) | 40 (48.4) |
Crypt distortion | 7 (17.5) | 40 (48.4) |
Others | 11 (27.5) | 40 (48.4) |
CT: computed tomography; OGD: esophago-gastro-duodenoscopy; MRI: magnetic resonance imaging.