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. 2018 Jun 2;4(6):524–527. doi: 10.1016/j.jdcr.2018.05.002

Table I.

Diagnostic criteria for DRESS syndrome according to RegiSCAR3, 4

No Yes Unknown
Fever ≥ 38.5°C −1 0 −1
Enlarged lymph nodes (≥2 sites, >1 cm) 0 1 0
Atypical lymphocytes 0 1 0
Eosinophilia 0 0
 0.7-1.499 × 109/L or 10%-19.9% 1
 ≥1.5 × 109/L or ≥20% 2
Skin rash 0 0
 Extent >50% 0 1 0
 At least 2 of edema, infiltration, purpura, scaling −1 1 0
 Biopsy suggesting DRESS −1 0 0
Internal organ involved 0 0
 1 1
 2 or more 2
Resolution in >15 d −1 0 −1
At least 3 biological investigations done and negative to exclude alternative diagnosis 0 1 0

Final score: <2, no cases; 2-3, possible case; 4-5, probable case; >5, definite case.