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Signalling differences as determined by RPPA in HCC1569 ERBB4 V721I- or ERBB4 S303F- (transfected) HER2-positive cell lines relative to matched HCC1569 cells transfected with WT ERBB4 normalized to 100.
* = p < 0.05 relative to matched ERBB4-WT cells. p-values were calculated using the Student’s t test (two-tailed with equal variance).
HER, human epidermal growth factor-like receptor; RPPA, reverse phase protein array; WT, wildtype.
