Table 3.
Effect of leptin and camel milk on brain lipid peroxidation, SOD, GPx and catalase in brain of rats treated with valproic acid-induced autism.
| Treatments | MDA (nM/mg protein) | SOD (U/mg protein) | GPx (U/mg protein) | Catalase (U/mg tissue) |
|---|---|---|---|---|
| Control | 33.45 ± 0.43a | 293.33 ± 14.85b | 30.06 ± 0.71a | 7.97 ± 0.18a |
| VPA | 84.77 ± 5.27b | 55.20 ± 4.21a | 5.65 ± 0.34b | 1.5 ± 0.09b |
| LEPT | 21.56 ± 1.25c | 217.29 ± 16.9c | 19.41 ± 1.36c | 5.15 ± 0.36c,f |
| CAM | 26.47 ± 1.25a | 231.01 ± 8.29c | 23.74 ± 0.91d | 6.3 ± 0.24d |
| VPA + LEPT (I) | 43.89 ± 1.75a | 101.63 ± 2.8a,d | 10.46 ± 0.41e | 2.77 ± 0.11e |
| VPA + LEPT (II) | 21.83 ± 1.42c | 164.5 ± 15.9d | 16.77 ± 1.09c, f | 4.45 ± 0.29f |
| VPA + CAM | 36.93 ± 1.76a | 148.4 ± 6.7d, e | 15.26 ± 0.73f | 4.05 ± 0.19f |
MDA: malondialdehyde; SOD: superoxide dismutase; GPx: glutathione peroxidase; VPA: valproic acid; LEPT: leptin; CAM: camel milk.
Within each column, means superscript with different letters are significantly different (P ⩽ 0.05).