Table 2.
Results of Univariable and Multivariable Logistic Regression Models and Risk Differences of Factors Associated With Acquisition of Multidrug-Resistant Tuberculosis Within 12 Months of Treatment, Russian Federation (n = 709)
| Factor | OR (95% CI) |
P | Adjusted OR (95% CI) |
P | RD, % (95% CI) |
Adjusted RD, % (95% CI) |
||||
|---|---|---|---|---|---|---|---|---|---|---|
| FAST cohort | 0.22 | (.11–.48) | <.001 | 0.16 | (.07–.39) | <.001 | −9.13 (−12.82 to −5.45) | −9.23 (−12.60 to −5.86) | ||
| Weeks in hospital (n = 706) | 1.09 | (1.06–1.11) | <.001 | 1.09 | (1.06–1.12) | <.001 | 0.10 | (.06–.15) | 0.11 | (.06–.16) |
| Male sex | 0.95 | (.51–1.78) | .90 | … | −0.34 | (−5.48–4.80) | … | |||
| Single marital statusa | 0.68 | (.40–1.16) | .15 | … | −3.03 | (−7.21–1.15) | … | |||
| Urban residence | 1.13 | (.64–1.97) | .66 | … | 1.03 | (−3.66–5.73) | … | |||
| Any incarceration history | 1.05 | (.50–2.21) | .88 | … | 4.50 | (−5.74–6.65) | … | |||
| Any smoking history (n = 705) | 1.29 | (.67–2.49) | .44 | … | 1.92 | (−2.69–6.53) | … | |||
| Alcohol use disordera | 1.46 | (.85–2.47) | .16 | … | 2.97 | (−1.21–7.25) | … | |||
| Bilateral and cavitary diseasea | 1.47 | (.87–2.46) | .15 | … | 3.16 | (−1.22–7.55) | … | |||
| Known prior tuberculosis | 3.55 | (1.82–6.88) | <.001 | 4.16 | (1.91–9.07) | <.001 | 14.98 | (4.38–25.59) | 13.70 | (3.97–23.44) |
| Known hepatitis diagnosis | 1.08 | (.53–2.19) | .99 | … | 0.63 | (−5.38–6.64) | … | |||
| Known HIV infection | 0.34 | (.04–2.55) | .29 | … | −5.82 | (−12.61–.96) | … | |||
| BMIa | 0.92 | (.85–1.01) | .07 | … | −0.57 | (−1.15–.10) | … | |||
| Age in y | 0.99 | (.97–1.01) | .39 | … | −0.06 | (−2.10–.08) | … | |||
Data are for 709 patients, unless otherwise indicated.
Abbreviations: BMI, body mass index; CI, confidence interval; HIV, human immunodeficiency virus; OR, odds ratio; RD, risk difference.
aIncluded in the initial model but not in the final model.