Table 1.
Case No. | Age, years/sex | Presenting symptom | Unilateral recurrent laryngeal nerve paralysis | Thyroid function (TSH, µIU/mL/FT4, ng/mL) | De novo | Stage at diagnosis | ECOG PS | Previous treatment |
Tracheotomy | ||
---|---|---|---|---|---|---|---|---|---|---|---|
surgery | chemotherapy | radioactive iodine | |||||||||
1 | 58/M | dysphagia and neck mass | no | Euthyroid 3.17/1.57 | yes | IVB | 0 | none | none | none | no |
2 | 69/M | aggressive metastases | yes | Euthyroid (levothyroxine) 0.802/1.94 | no (anaplastic change of PDC) | IVC | 0 | TTX | none | 6 cycles | no |
3 | 61/M | neck mass | yes | Euthyroid 0.79/1.43 | yes | IVC | 0 | none | none | none | no |
4 | 51/M | hoarseness | yes | Euthyroid 1.82/1.01 | yes | IVC | 0 | none | none | none | no |
5 | 50/M | hoarseness and pharyngeal pain | yes | Euthyroid 2.18/1.19 | yes | IVC | 0 | none | C-mab + FP | none | yes |
PDC, poorly differentiated thyroid cancer; TTX, total thyroidectomy; C-mab, cetuximab; FP, CDDP + 5FU.