Table 1.

Overview of the current literature on NF1 with concurrent thyroid disease

Study	Subjects (n = 1)	Methods	Outcome
Gorgel et al. [11]	NF1 + GIST + pheochromocytoma	Thryoid US Fine needle aspiration biopsy	Multifocal papillary thyroid carcinoma Cervical lymph node metastases
Kim et al. [12]	NF1	Thyroid US FNA biopsy	Papillary thyroid carcinoma
Koksal et al. [13]	NF 1	Thyroid US Total thyroidectomy	Follicular papillary thyroid carcinoma Neurofibroma
Gkaliagkhousi et al. [14]	NF1 + pheochromocytoma	Investigation for other pheochromocytoma-related syndromes	Hyperparathyroidism Medullary thyroid cancer (MEN 2A) Germline mutation for NF1 but not RET
Hashiba et al. [15]	NF1 + papillary thyroid cancer + pheochromocytoma	Head CT + MRI + angiography Histologic examination	Skull metastasis from papillary thyroid cancer
Yoshida et al. [16]	NF1 + lung metastasis of malignant schwannoma	Autopsy	Carcinoid tumor in duodenum Medullary thyroid carcinoma Diffuse adrenal medullary hyperplasia
Faraz et al. [17]	NF1	Laboratory investigation	Autoimmune hypothyroidism
Nabi et al. [18]	NF1	Thyroid US FNA Laboratory investigation	Hashimoto thyroiditis
Nanda [19]	NF1	-	Autoimmune thyroiditis
Bolko et al. [20]	NF1 + Noonan	Laboratory investigation Thyroid US Radioisotope scan Thyroid iodine uptake	Graves disease

NF1, neurofibromatosis type 1; US, ultrasonography; CT, computed tomography.