Table 2.
The mean and standard deviation (SD) of the variables of interest in each group. The p-values are based on a two-sample t-test for T_Peak and log10 (Dose_CEM43), and based on a Mann-Whitney test for Dose_CEM43. The threshold was statistically chosen by maximizing both sensitivity and specificity. It was found that the threshold T_Peak = 46 yielded 83% sensitivity and 75% specificity based on our data. Similarly, the threshold Dose_CEM43 = 12.6 yielded 86% sensitivity and 88% specificity.
| Variable | Negative (N=11) | Positive (N=26) | P-value | ||
|---|---|---|---|---|---|
|
| |||||
| Mean | SD | Mean | SD | ||
| T_Peak | 45.9 | 1.1 | 48.6 | 1.9 | <0.001 |
| Dose_CEM43 | 17.3 | 20.1 | 159.3 | 363.7 | <0.001 |
| log10(Dose_CEM43) | 1.038 | 0.440 | 1.831 | 0.499 | <0.001 |