Expression of Cx43 in N-cadherin CKO hearts. Heart ventricles from wild-type (A, B) and N-cadherin CKO (C, D) animals seven weeks post-tamoxifen treatment were co-immunostained for N-cadherin (A, C) and Cx43 (B, D). N-cadherin was lost from the intercalated discs in the CKO heart, while Cx43 (D) was significantly decreased in the ventricular myocardium. Bar, 50 μm. Reprinted with permission from Ref. [36].