Table 2.

CRC Simulation Modules and Relevant Input Data Sources

Module	Input Data Sources
Clinical or health policy intervention scenarios	Literature reviews Stakeholder interviews
Healthy lifestyle	Behavioral Risk Factor and Surveillance System National Health Interview Survey National Health and Nutrition Examination Survey Claims data (Medicare, Medicaid, Commercial/Private)
The population	US census US life tables American Community Survey Public Use Microdata Sample RTI synthetic population
Healthcare infrastructure	Area Resource File State Medical Facilities Plan Health insurance claims data American Hospital Association Federally Qualified Health Centers Area Health Education Centers
Cancer screening, diagnosis, treatment, & surveillance	Behavioral Risk Factor and Surveillance System National Health Interview Survey National Health and Nutrition Examination Survey Claims data (Medicare, Medicaid, Commercial/Private) Clinical guidelines (e.g., ACG and USPSTF) Area Resource File State Medical Facilities Plan
Natural history of cancer	Epidemiologic data/models Clinical evidence Literature reviews Expert and/or stakeholder interviews Cancer registries