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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Expert Opin Ther Targets. 2018 May 9;22(6):467–486. doi: 10.1080/14728222.2018.1472241

Table 1.

Anti-leishmanial activities of some plant products/compounds.

Plant products/
compounds
Standard Drug Plant Species References
Oxylipin (Polyacetylene) Flavonoids Oxylipin (3S)-16, 17-didehydrofalcarinol Tridax procumbens L.mexicana [304]
Flavonoids Luteolin Vitex negundo L.donovani [305]
Quercetin Fagopyrum esculentum L.donovani [306]
Quercetin and its derivatives Kalanchoe pinnata L.amazonensis [307]
Quercetin Kalanchoe pinnata L. chagasi [308]
Ethanolic extract Piper betle L. L.donovani [309]
Methanolic extract Piper betle L. L.donovani [310]
 2′′-acetylpetiolaroside Delphinium staphisagria L. infantum and L.braziliensis [311]
Guaianolide Tanacetum parthenium (L.)
Schultz Bip
L. amazonensis [312]
Quercetin3-O-methyl ether Strychnos pseudoquina L. amazonensis [313]
Plant extract Bidens pilosa L. and Punica granatum L L. amazonensis [314]
Alkaloids N-Methyltetrahydroberberinium iodide Enantia chlorantha L.donovani [315]
Ancistroealaine A Ancistrocladus ealaensis L.donovani [316]
Quinoline alkaloid Galipea longiflora L.amazonensis [317]
 2-n-Propylquinoline L.amazonensis [318]
Julocrotine, a glutarimide alkaloid Croton pullei var. Glabrio L. amazonensis [319]
Methanol extract Nuphar lutea L.major [320]
Quinolinic alkaloid Galipea longiflora L.amazonensis [321]
Ethanolic extract Senna Spectabilis L.major [322]
Bisbenzylisoquinoline Cissampelos sympodialis Eichl. L. chagasi [323]
Furoquinoline alkaloids Helietta apiculata L.amazonensis [324]
Securinega alkaloids Margaritaria nobilis L.amazonensis [325]
Dicentrinone Duguetia furfuracea [326]
Terepenoids Triterepenoid extract Trichosanthes dioica L.donovani [327]
Sesquiterepene lactone-rich dicholomethane fraction Tanacetum parthenium L.amazonensis [328]
Oleanolic- and ursolic-containing titerpenic fraction Baccharis uncinella L.amazonensis and L.braziliensis [329]
Taxodione Salvia deserta L.donovani [330]
Artemisinin Artemisia annua L.major [331]
Abietane diterpenoids Taxodium distichum L.donovani and L.amazonensis [332]
trans-dehydrocrotonin Croton cajucara Benth. L.amazonensis [333]
Chalcones Licochalcone A Chinese liquorice L.major [334]
L. donovani [335]
20 naturally occurring chalcones Piper aduncum L. donovani [336]
Adunchalcone Piper aduncum L. L.amazonensis, L.braziliensis and L.chagasi [337]
Dihydrochalcones Piper elongatum L.braziliensis [338]
Quinones Plumbagin Pera benensis L.amazonensis [339, 340]
3,3_-Biplumbagin
1-Acetylbenzoisochromanquinone Cephaelis camponutans L.donovani [341]
N-Methylliriodendronine Stephania dinklagei L.donovani [342]
2-methyl-5 -(3′-methyl-but-2′-enyloxy)-[1,4]naphthoquinone (1) Plumbago zeylanica L.donovani [343]
Methanolic extract Nigella sativa L L.tropica and L.infantum [344]
Saponin Hederagenin Ivy Hedera helix L.tropica and L.infantum [345]
α-Hederin
β-Hederin
Hederacolchiside A1
Hedera colchica L.mexicana [346]
Maesasaponin V.3 and VI.2 Maesa balansae
Maesa lanceolata
L.infantum [347]
Maesabalides III
Maesabalides IV
Maesa balansae L.infantum [348]
Lignan Diphyllin Haplophyllum bucharicum L.infantum [349]
Neolignan 2,3-dihydrobenzofuran Propolis L.amazonensis [350]
4-Aminoquinoline AMQ-j L.amazonensis [351]
[352]
N-cinnamoylated amioquinoline L.infantum
[353]
7-cholro 4- quinolinylhydraz one L.amazonensis
8-hydroxyquinoline [354]
1,2,3-triazole salts
(Bioisosteres)
L.amazonensi s,L.braziliensi
s,L.infantum
[355]
L.amazonensis
N-benzyl- 1-Hbenzimidazole L.mexicana, L.donovani, L.braziliensis [356]