Table 3.
Changes in body weight and adiposity markers of metabolic syndrome patients maintained on Met and treated with GKB extract
| Parameters | Met + placebo (n=18)
|
Met + GKB (n=22)
|
||
|---|---|---|---|---|
| Baseline | 90 days | Baseline | 90 days | |
| BMI (kg/m2) | 34.2±5.6 | 33.7±5.7 | 36.3±4.9 | 33.9±5.1* |
| WC (cm) | 102.7±7.6 | 105.1±8.4* | 109.9±8.0 | 106.7±7.0* |
| VAI | 203.8±59.4 | 210.8±48.6 | 237.7±81.2 | 182.6±74.7* |
| Serum leptin (ng/mL) | 7.9±1.7a | 6.7±2.1a | 8.3±1.1a | 4.7±0.6*,b |
Notes: Values are mean ± SD. GKB, 120 mg GKB extract. Values with nonidentical superscripts (a and b) among groups are significantly different (ANOVA, P<0.05).
*
Significantly different from baseline in each group (paired t-test, P<0.05).
Abbreviations: ANOVA, analysis of variance; BMI, body mass index; GKB, Ginkgo biloba; Met, metformin; VAI, visceral adiposity index; WC, waist circumference.