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The tumor volume (A), body weight (B), and H and E staining of tumor tissue (C) analysis of MCF-7 ADR tumor-bearing BALB/c mice after intravenous administration of different formulations (saline, DNLC, LNLC and LDNLC). **P < 0.01 versus LDNLC. Data were expressed as mean ± SD (n = 6).
Abbreviations: DNLC, DOX mono-delivery NLC; LNLC, Lapa mono-delivery NLC; LDNLC, NLC co-delivering Lapa and DOX; DOX, doxorubicin; NLC, nanostructured lipid carrier; Lapa, β-lapachone.
