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. 2018 Jun 29;9(50):29495–29507. doi: 10.18632/oncotarget.25685

Figure 1. WES and IPA analysis reveals relevant biological targets of HCC in HepPten- mice.

Figure 1

(A) IPA results of the 162 genes identified mutated in HCC tumors in HepPten- mice. Core analysis on IPA identified top upstream regulators and causal networks for the dataset. (B) Percentage of HepPten- mice that carried a mutation in at least one of the target genes for each identified upstream regulator. (C) Percentage of HCC patients in TCGA that carried a mutation in at least one of the target genes for each identified upstream regulator.