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. Author manuscript; available in PMC: 2018 Jul 24.
Published in final edited form as: Nature. 2018 Jan 24;555(7694):107–111. doi: 10.1038/nature25757

Figure 3. Effect of SIRLOIN sequence changes on element activity.

Figure 3

a, Localization (top) and expression levels (bottom) for sequence variants that are identical to JPX#9 except for the indicated base change. Horizontal gray line indicates the corresponding level for the wt sequence. b, Localization for sequences where the indicated number of bases were scrambled with C↔G and A↔T changes. The position of the point indicates the first base of the scrambled region.