Table 11. Cox regression univariate and multivariate analysis for prediction of death (reader 1).
| Univariate analysis | Multivariate analysis (model 1) |
Multivariate analysis (model 2) | |||||
|---|---|---|---|---|---|---|---|
| n | OR [95% CI] | p | OR [95% CI] | p | OR [95% CI] | p | |
| Age < median | 28 | 1.31 [0.62–2.77] | 0.47 | 1.35 [0.60–3.03] | 0.46 | 1.52 [0.67–3.46] | 0.30 |
| Phenotype | 0.08 | 0.04 | 0.12 | ||||
| HER2 | 9 | 1 | 1 | 1 | |||
| Luminal | 41 | 6.72 [0.87–52.2] | 0.06 | 6.22 [0.77–50.5] | 0.08 | 5.34 [0.66–43.5] | 0.11 |
| Triple negative | 7 | 11.88 [1.31–107.4] | 0.02 | 14.78 [1.59–137.1] | 0.02 | 10.2 [1.03–100.8] | 0.04 |
| Metabolic response (EORTC) | 0.04 | 0.03 | - | ||||
| CMR | 22 | 1 | 1 | ||||
| PMR | 17 | 3.2 [1.17–8.75] | 0.02 | 3.51 [1.24–9.9] | 0.02 | - | - |
| SMD | 12 | 1.56 [0.30–8.08] | 0.59 | 1.32 [0.25–6.97] | 0.74 | - | - |
| PMD | 6 | 4.13 [1.38–12.35] | 0.01 | 4.46 [1.43–13.9] | 0.01 | - | - |
| Metabolic response (PERCIST) | 0.006 | - | 0.01 | ||||
| CMR | 20 | 1 | 1 | ||||
| PMR | 12 | 4.51 [1.45–14.0] | 0.008 | - | - | 5.33 [1.64–17.4] | 0.004 |
| SMD | 15 | 1.69 [0.44–6.48] | 0.43 | - | - | 1.8 [0.45–7.11] | 0.39 |
| PMD | 10 | 7.07 [2.13–23.4] | 0.001 | - | - | 5.9 [1.7–20.5] | 0.004 |
| SBR III | 24 | 1.08 [0.55–2.12] | 0.83 | - | - | - | - |
| De novo MBC | 18 | 1.01 [0.46–2.23] | 0.97 | - | - | - | - |
SBR III: Grade 3 tumors of Scarff-Bloom-Richardson grading system corresponding to a high grade breast cancer with aggressive potential