Table 12. Summary of EORCT and PERCIST evaluation methods.

	EORTC	PERCIST
Measurable parameters/lesions
Measurable lesion (threshold definition)	Viable tumor (SUV> surrounding background)	SULpeak >1.5 liver SULmean + 2DS
Target lesions	Viable tumors; no number given (5 in study)	Highest SULpeak lesion (1 lesion)
Measured parameter for metabolic response evaluation	ΔΣSUVmax target lesions	ΔΣSULpeak target lesion
Response criteria
CMR	No viable tumor	No lesion above > threshold
PMR	Reduction of minimum of 25% in ΔΣSUVmax	Reduction of minimum of 30% in target measurable tumor 18F-FDG SUL peak
SMD	Not CMR, PMD or PMR	Not CMR, PMD or PMR
PMD	Increase in ΔΣSUVmax >25% or new lesion	Increase in SULpeak >30% or new lesion

EORTC = European Organization for Research and Treatment of Cancer; PERCIST = PET Response Criteria in solid Tumours; CMR = Complete metabolic response; PMR = Partial metabolic response; SMD = Stable metabolic disease; PMD = Progressive metabolic disease