Skip to main content
. 2018 Jul 11;5(5):e477. doi: 10.1212/NXI.0000000000000477

Figure 2. Annualized qualifying relapse rate over the double-blind period: Amended protocol intent-to-treat population.

Annualized qualifying relapse rate = (total number of qualifying relapses / total time on study during the double-blind period) × 365.25. p-Value based on Wald Chi-square from the number of qualifying relapses using a Poisson regression model with fixed effects for treatment group and IFN-β treatment and with log of time on study during the double-blind period as an offset. All efficacy analyses were exploratory as the study was not powered to detect between-group differences for any endpoint and all p values less than 0.05 are considered as nominally significant. IFN = interferon

Figure 2