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. Author manuscript; available in PMC: 2018 Jul 16.
Published in final edited form as: J Am Coll Surg. 2018 Feb 7;226(4):596–603. doi: 10.1016/j.jamcollsurg.2017.12.052

Table 1.

Inherited Syndromes and Associated Lifetime Risk of Pancreatic Ductal Adenocarcinoma

Inherited syndrome Lifetime risk of pancreatic cancer
Hereditary breast and ovarian cancer syndrome, RR* 3.5–5.9
Peutz-Jeghers syndrome, % 11–36
Hereditary pancreatitis, % 25–40
Hereditary nonpolyposis colorectal cancer syndrome (Lynch syndrome), % 3.7
Familial atypical multiple mole melanoma, % 17
Familial adenomatous polyposis, % 1.7
*

Relative risk (RR) associated with BRCA2 specifically. Data obtained from multiple sources.5,6