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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Radiat Res. 2018 May 10;190(1):53–62. doi: 10.1667/RR14990.1

FIG. 2.

FIG. 2

Heat map illustrating the patterns of upstream regulator activation in response to LD50/30 as predicted by IPA analysis. Each row across represents a potential regulator of the gene expression patterns observed. Each column represents a genotype exposed to LD50/30: WT (8.8 Gy) and Parp1−/− (6 Gy). The responses are shaded according to the scale bar to represent the z-score associated with the prediction of response. A z-score ≥ 2 represents a significant prediction of activation (red) and a z-score ≤ −2 represents a significant prediction of inhibition (blue).