Table 3.

Baseline clinical and haemodynamic characteristics between patients with PAH and other groups of PH, from both discovery and validation cohorts

Variable	PAH (n = 50)	PH (other than PAH) (n = 41)	P-value
Age (years)	57 ± 14	57 ± 14	0.87
Female, n (%)	34 (68%)	26 (63%)	0.65
Mean PAP (mm Hg)	46 ± 13	37 ± 11	0.001
PVR (Wood units)	8.3 ± 5.3	3.5 ± 2.3	<0.0001
TD cardiac output (L/min)	4.7 ± 1.5	5.7 ± 2.4	0.03
S100A12 (ng/mL)	32.6 ± 15.8	30.9 ± 16.3	0.62
Survival (years)	2.4 ± 1.0	2.3 ± 1.3	0.97

Results are reported as mean ± SD, unless otherwise stated.

P-values were calculated using the Fisher’s exact test except for age, mean PAP, TD cardiac output, where unpaired Student’s t-test was used.

PAH, pulmonary arterial hypertension; PAP, pulmonary artery pressure; PH, pulmonary hypertension; PVR, pulmonary vascular resistance; TD, thermodilution.