Table 2.
Normal Controls (N=142) |
Baseline (N=63) | 1 year (N=68) | 3 years (N=51) | 5 years (N=36) | |||||
---|---|---|---|---|---|---|---|---|---|
Circumferential Strain | p-value* | p-value* | p-value* | p-value* | |||||
|
|
|
|
||||||
Global circumferential strain | −24.27 (−21.91, −28.03) | −27.3 (−23.87, −30.01) | 0.005 | −23.64 (−19.96, −26.79) | 0.241 | −22.51 (−20.86, −26.87) | 0.252 | −24.36 (−21.41, −28.43) | 0.949 |
Average circumferential strain rate | −1.45 (−1.25, −1.65) | −1.74 (−1.47, −1.98) | <0.001 | −1.43 (−1.16, −1.67) | 0.166 | −1.43 (−1.19, −1.56) | 0.160 | −1.35 (−1.2, −1.61) | 0.136 |
Peak diastolic circumferential strain rate | 1.51 (1.29, 1.71) | 1.69 (1.38, 2.06) | 0.002 | 1.55 (1.38, 1.85) | 0.145 | 1.55 (1.29, 1.85) | 0.277 | 1.62 (1.31, 1.82) | 0.271 |
Longitudinal Strain | |||||||||
Global longitudinal strain | −19.18 (−17.31, −21.61) | −14.59 (−11.11, −17.59) | <0.001 | −18.15 (−16.12, −21.67) | 0.272 | −19.44 (−16.19, −21.63) | 0.825 | −19.04 (−16.06, −21.57) | 0.900 |
Average longitudinal strain rate | −1.03 (−0.9, −1.26) | −0.84 (−0.7, −1.09) | <0.001 | −1.06 (−0.93, −1.24) | 0.679 | −0.95 (−0.86, −1.17) | 0.062 | −1.07 (−0.86, −1.29) | 0.965 |
Peak diastolic longitudinal strain rate | 1.25 (1.05, 1.47) | 0.98 (0.69, 1.24) | <0.001 | 1.32 (1.09, 1.58) | 0.209 | 1.39 (1.04, 1.62) | 0.272 | 1.33 (1.12, 1.6) | 0.184 |
p-values from the Wilcoxon Rank Sum test for pairwise comparison of each time point with the normal control group
Data expressed as median (25%, 75%)