Table.
Eye # | Age | M/F | Uveitis dx (years) | Uveitis Diagnosis | Prior edema treat. | Systemic meds | Topical meds | Study interval (days) | VA 1 | VA 2 | CST 1 | CST 2 | Change CST (um) | (%) | Side Effects |
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BILATERAL
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1R | 52 | F | 7.1 | Idiopathic intermediate | none | none | none | 35.0 | 20/25 | 20/30 | 400 | 370 | 30 | 8 | C, DI, F, N |
1L | PA, K, STTA | K QID, PA QID | 20/80 | 20/60 | 498 | 353 | 145 | 29 | |||||||
2R | 63 | M | 0.3 | Idiopathic intermediate | D, Pred | Pred 10 mg | D BID | 20.0 | 20/40 | 20/30 | 455 | 440 | 15 | 3* | DI, DY, HL |
2L | D, Pred | D BID | 20/40 | 20/30 | 488 | 431 | 57 | 12* | |||||||
3R | 70 | F | 0.2 | Pseudophakic macular edema | PA, D, K | none | none | 55.0 | 20/32 | 20/30 | 393 | 386 | 7 | 2 | DE, ED, HY, MA |
3L | PA, D, K | none | 20/70 | 20/30 | 499 | 408 | 91 | 18 | |||||||
UNILATERAL
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7R | 24 | M | 0.9 | HLA-B27 AU | PA | Pred 20 mg | D QID, N TID | 14.0 | 20/50 | 20/20 | 767 | 362 | 405 | 53 | none |
8L | 67 | M | 10.5 | Idiopathic AU | D, N | none | D QID, N TID | 30.0 | 20/50 | 20/30 | 585 | 341 | 244 | 42 | none |
9R | 61 | F | 3.0 | Anterior and posterior scleritis | D, N, Pred | MTX 15 mg, Pred 20 mg | D 6× a day, N TID | 39.0 | 20/125 | 20/60 | 595 | 376 | 219 | 37 | IA, PR |
10L | 20 | M | 1.4 | DUSN | STTA | none | none | 21.0 | 20/32 | 20/25 | 583 | 374 | 209 | 36 | DY, PR |
11R | 68 | F | 3.1 | Prior ARN | N, PA, IB, PPV/MP | MTX 25 mg | D QID | 30.0 | 20/50 | 20/50 | 471 | 310 | 161 | 34 | DI, G, PR |
12R | 72 | F | 1.8 | Chronic AU | D, K | none | PA TID | 28.0 | 20/50 | 20/30 | 399 | 251 | 148 | 37 | PR |
13L | 38 | F | 27.5 | JIA associated AU | PA | none | PA BID | 28.0 | 20/125 | 20/40 | 449 | 318 | 131 | 29 | DY, ML, PR |
14L | 79 | M | 1.4 | Pseudophakic macular edema | PA, IVTA, IB | none | none | 43.0 | 20/100 | 20/100 | 573 | 444 | 129 | 23 | C, F, DY, PR |
15R | 65 | F | 2.4 | Birdshot choroiditis | PA, D, K, N, STTA, Pred | MTX 15mg, Pred 20mg, | D QID, N TID | 28.0 | 20/40 | 20/40 | 390 | 337 | 53 | 14 | F, DI, DY, PR |
16L | 58 | F | 4.1 | HLA-B27 AU | D, N, STTA, IVTA, | Humira 40mg Q 2 wk | D QID, N QID | 35.0 | 20/40 | 20/30 | 341 | 305 | 36 | 11* | F, DY, PO, PR |
17L | 52 | M | 5.8 | Sarcoidosis | PA, D, STTA, Pred, PPV/MP | MTX 25mg, AZA 100 mg, Pred 10 mg | D QID, | 38.0 | 20/40 | 20/30 | 385 | 357 | 28 | 7 | none |
18L | 81 | M | 2.5 | Pseudophakic macular edema | PA | none | PA BID, | 42.0 | 20/40 | 20/40 | 327 | 302 | 25 | 8* | PR |
19L | 46 | F | 3.7 | Demyelination associated | D, N | none | D TID, N BID | 21.0 | 20/50 | 20/50 | 366 | 342 | 24 | 7 | F, PR |
Complete resolution of macular edema
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Treatment/Medications | Diagnosis | Side effects | Other |
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PA= 1% Prednisolone acetate D= 0.5% Difluprednate Pred= Oral prednisone N= 0.1 % Nepafenac K= 0.5% Ketorolac STTA= Subtenons triamcinolone IB= Intravitreal bevacizumab IVTA= Intravitreal triamcinolone AZA= Azathioprine MTX= Methotrexate PPV/MP= Pars plana vitrectomy with internal limiting membrane peel BID= Twice a day TID= Three times a day QID= Four times a day |
ARN= Acute retinal necrosis AU= Anterior Uveitis DUSN= Diffuse unilateral subacute neuroretinitis HLAB27= human leukocyte antigen B27 JIA= Juvenile Idiopathic Arthritis associated |
C= Confusion/Disorientation DE= Dehydration DI= Diarrhea DY= Dysguesia ED= Emergency visit F= Fatigue G= Gastroesophageal reflux HL= Hearing Loss HY= Hypotension IA= Increased Appetite MA= Malaise ML= Memory Loss N= Nausea PO= Polydipsia PR= Paresthesia |
CST= Central subfield thickness VA= Visual acuity CAI= Carbonic anhydrase inhibitor SE= Side effect D/C= Discontinuation IC= Insurance Coverage |
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