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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Retina. 2019 May;39(5):948–955. doi: 10.1097/IAE.0000000000002044

Table.

Demographics and characteristics of subjects with inflammatory macular edema treated with acetazolamide.

Eye # Age M/F Uveitis dx (years) Uveitis Diagnosis Prior edema treat. Systemic meds Topical meds Study interval (days) VA 1 VA 2 CST 1 CST 2 Change CST (um) (%) Side Effects
BILATERAL
1R 52 F 7.1 Idiopathic intermediate none none none 35.0 20/25 20/30 400 370 30 8 C, DI, F, N
1L PA, K, STTA K QID, PA QID 20/80 20/60 498 353 145 29
2R 63 M 0.3 Idiopathic intermediate D, Pred Pred 10 mg D BID 20.0 20/40 20/30 455 440 15 3* DI, DY, HL
2L D, Pred D BID 20/40 20/30 488 431 57 12*
3R 70 F 0.2 Pseudophakic macular edema PA, D, K none none 55.0 20/32 20/30 393 386 7 2 DE, ED, HY, MA
3L PA, D, K none 20/70 20/30 499 408 91 18
UNILATERAL
7R 24 M 0.9 HLA-B27 AU PA Pred 20 mg D QID, N TID 14.0 20/50 20/20 767 362 405 53 none
8L 67 M 10.5 Idiopathic AU D, N none D QID, N TID 30.0 20/50 20/30 585 341 244 42 none
9R 61 F 3.0 Anterior and posterior scleritis D, N, Pred MTX 15 mg, Pred 20 mg D 6× a day, N TID 39.0 20/125 20/60 595 376 219 37 IA, PR
10L 20 M 1.4 DUSN STTA none none 21.0 20/32 20/25 583 374 209 36 DY, PR
11R 68 F 3.1 Prior ARN N, PA, IB, PPV/MP MTX 25 mg D QID 30.0 20/50 20/50 471 310 161 34 DI, G, PR
12R 72 F 1.8 Chronic AU D, K none PA TID 28.0 20/50 20/30 399 251 148 37 PR
13L 38 F 27.5 JIA associated AU PA none PA BID 28.0 20/125 20/40 449 318 131 29 DY, ML, PR
14L 79 M 1.4 Pseudophakic macular edema PA, IVTA, IB none none 43.0 20/100 20/100 573 444 129 23 C, F, DY, PR
15R 65 F 2.4 Birdshot choroiditis PA, D, K, N, STTA, Pred MTX 15mg, Pred 20mg, D QID, N TID 28.0 20/40 20/40 390 337 53 14 F, DI, DY, PR
16L 58 F 4.1 HLA-B27 AU D, N, STTA, IVTA, Humira 40mg Q 2 wk D QID, N QID 35.0 20/40 20/30 341 305 36 11* F, DY, PO, PR
17L 52 M 5.8 Sarcoidosis PA, D, STTA, Pred, PPV/MP MTX 25mg, AZA 100 mg, Pred 10 mg D QID, 38.0 20/40 20/30 385 357 28 7 none
18L 81 M 2.5 Pseudophakic macular edema PA none PA BID, 42.0 20/40 20/40 327 302 25 8* PR
19L 46 F 3.7 Demyelination associated D, N none D TID, N BID 21.0 20/50 20/50 366 342 24 7 F, PR
*

Complete resolution of macular edema

Abbreviations:

Treatment/Medications Diagnosis Side effects Other

PA= 1% Prednisolone acetate
D= 0.5% Difluprednate
Pred= Oral prednisone
N= 0.1 % Nepafenac
K= 0.5% Ketorolac
STTA= Subtenons triamcinolone
IB= Intravitreal bevacizumab
IVTA= Intravitreal triamcinolone
AZA= Azathioprine
MTX= Methotrexate
PPV/MP= Pars plana vitrectomy with internal limiting membrane peel
BID= Twice a day
TID= Three times a day
QID= Four times a day
ARN= Acute retinal necrosis
AU= Anterior Uveitis
DUSN= Diffuse unilateral subacute neuroretinitis
HLAB27= human leukocyte antigen B27
JIA= Juvenile Idiopathic Arthritis associated
C= Confusion/Disorientation
DE= Dehydration
DI= Diarrhea
DY= Dysguesia
ED= Emergency visit
F= Fatigue
G= Gastroesophageal reflux
HL= Hearing Loss
HY= Hypotension
IA= Increased Appetite
MA= Malaise
ML= Memory Loss
N= Nausea
PO= Polydipsia
PR= Paresthesia
CST= Central subfield thickness
VA= Visual acuity
CAI= Carbonic anhydrase inhibitor
SE= Side effect
D/C= Discontinuation
IC= Insurance Coverage