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. 2018 Jul 16;8:10713. doi: 10.1038/s41598-018-28281-5

Figure 2.

Figure 2

EV71-specific IgA titres in nasal wash, BALF, and faeces. Mice were intranasally immunised with PBS, formalin-inactivated EV71 (5 μg/dose), or formalin-inactivated EV71 (5 μg/dose) plus CpG (20 μg/dose) three times at 3-week intervals. ELISA was used to measure EV71-specific IgA in the nasal wash (a), BALF (b), and faeces (c) of mice at 2 weeks after the third immunisation. Values shown are means ± SEMs of six mice in each experimental group; *p < 0.05, **p < 0.01. One representative study of three with similar results is shown. BALF: bronchoalveolar lavage fluid.